apoe3 ipsc line Search Results


2018 apoe4 apoe4 parental human ipsc line coriell ag10788 apoe3 apoe3 isogenic human ipsc line lin  (ATCC)
97
ATCC 2018 apoe4 apoe4 parental human ipsc line coriell ag10788 apoe3 apoe3 isogenic human ipsc line lin
2018 Apoe4 Apoe4 Parental Human Ipsc Line Coriell Ag10788 Apoe3 Apoe3 Isogenic Human Ipsc Line Lin, supplied by ATCC, used in various techniques. Bioz Stars score: 97/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 97 stars, based on 1 article reviews
2018 apoe4 apoe4 parental human ipsc line coriell ag10788 apoe3 apoe3 isogenic human ipsc line lin - by Bioz Stars, 2026-03
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apoe3 ipsc line  (Alstem Inc)
90
Alstem Inc apoe3 ipsc line
Apoe3 Ipsc Line, supplied by Alstem Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 90 stars, based on 1 article reviews
apoe3 ipsc line - by Bioz Stars, 2026-03
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human ips cell line (episomal, cd34+, apoe knockout) alstem cell advancement ips36  (Alstem Inc)
90
Alstem Inc human ips cell line (episomal, cd34+, apoe knockout) alstem cell advancement ips36
Human Ips Cell Line (Episomal, Cd34+, Apoe Knockout) Alstem Cell Advancement Ips36, supplied by Alstem Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/human ips cell line (episomal, cd34+, apoe knockout) alstem cell advancement ips36/product/Alstem Inc
Average 90 stars, based on 1 article reviews
human ips cell line (episomal, cd34+, apoe knockout) alstem cell advancement ips36 - by Bioz Stars, 2026-03
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human ipsc line from a healthy control ( apoe3)  (Jackson Laboratory)
90
Jackson Laboratory human ipsc line from a healthy control ( apoe3)

Human Ipsc Line From A Healthy Control ( Apoe3), supplied by Jackson Laboratory, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 90 stars, based on 1 article reviews
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ipsc line  (Coriell Institute for Medical Research)
90
Coriell Institute for Medical Research ipsc line
Extracellular cholesterol positively regulates the formation of lipid rafts and its association with APP in hiPSC-derived neurons (A) Measurement of secretory levels of cholesterols in <t>ApoE3</t> or ApoE4 ACM. (B) Filipin III signals in ACM (n = 4 experiments). (C) Levels of total cholesterol, free cholesterol, and cholesteryl ester in ACM (n = 3 experiments). (D) Images of filipin III staining in neurons. Scale bar, 10 μm. Right: quantification of filipin III area, intensity, and area × intensity in neurons (n = 13–15 images from three experiments). (E) Images of CTX-B and APP staining in neurons. Scale bar, 10 μm. (F) CTX-B area, intensity, and area × intensity in neurons (n = 12 images from three experiments). (G) APP area, intensity, and area × intensity in neurons (n = 12 images from three experiments). (H) Co-localization of CTX-B and APP in neurons (n = 12 images from three experiments). (I) APP intensity in CTX-B/APP co-localization area in neurons (n = 12 images from three experiments). ∗ p < 0.05, ∗∗ p < 0.01, ∗∗∗ p < 0.001, ∗∗∗∗ p < 0.0001; ns, not significant (Student's t test or ANOVA followed by Dunnett's post hoc test). Error bars represent SEM.
Ipsc Line, supplied by Coriell Institute for Medical Research, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Image Search Results


Journal: iScience

Article Title: Imaging lipid rafts reveals the principle of ApoE4-induced Aβ upregulation in human neurons

doi: 10.1016/j.isci.2025.111893

Figure Lengend Snippet:

Article Snippet: Human iPSC line from a healthy control ( APOE3 ) , The Jackson Laboratory , Cat#JIPC1000.

Techniques: Recombinant, Membrane, Electron Microscopy, Enzyme-linked Immunosorbent Assay, Conjugation Assay, Control, Software

Extracellular cholesterol positively regulates the formation of lipid rafts and its association with APP in hiPSC-derived neurons (A) Measurement of secretory levels of cholesterols in ApoE3 or ApoE4 ACM. (B) Filipin III signals in ACM (n = 4 experiments). (C) Levels of total cholesterol, free cholesterol, and cholesteryl ester in ACM (n = 3 experiments). (D) Images of filipin III staining in neurons. Scale bar, 10 μm. Right: quantification of filipin III area, intensity, and area × intensity in neurons (n = 13–15 images from three experiments). (E) Images of CTX-B and APP staining in neurons. Scale bar, 10 μm. (F) CTX-B area, intensity, and area × intensity in neurons (n = 12 images from three experiments). (G) APP area, intensity, and area × intensity in neurons (n = 12 images from three experiments). (H) Co-localization of CTX-B and APP in neurons (n = 12 images from three experiments). (I) APP intensity in CTX-B/APP co-localization area in neurons (n = 12 images from three experiments). ∗ p < 0.05, ∗∗ p < 0.01, ∗∗∗ p < 0.001, ∗∗∗∗ p < 0.0001; ns, not significant (Student's t test or ANOVA followed by Dunnett's post hoc test). Error bars represent SEM.

Journal: Stem Cell Reports

Article Title: APOE4 -carrying human astrocytes oversupply cholesterol to promote neuronal lipid raft expansion and Aβ generation

doi: 10.1016/j.stemcr.2021.07.017

Figure Lengend Snippet: Extracellular cholesterol positively regulates the formation of lipid rafts and its association with APP in hiPSC-derived neurons (A) Measurement of secretory levels of cholesterols in ApoE3 or ApoE4 ACM. (B) Filipin III signals in ACM (n = 4 experiments). (C) Levels of total cholesterol, free cholesterol, and cholesteryl ester in ACM (n = 3 experiments). (D) Images of filipin III staining in neurons. Scale bar, 10 μm. Right: quantification of filipin III area, intensity, and area × intensity in neurons (n = 13–15 images from three experiments). (E) Images of CTX-B and APP staining in neurons. Scale bar, 10 μm. (F) CTX-B area, intensity, and area × intensity in neurons (n = 12 images from three experiments). (G) APP area, intensity, and area × intensity in neurons (n = 12 images from three experiments). (H) Co-localization of CTX-B and APP in neurons (n = 12 images from three experiments). (I) APP intensity in CTX-B/APP co-localization area in neurons (n = 12 images from three experiments). ∗ p < 0.05, ∗∗ p < 0.01, ∗∗∗ p < 0.001, ∗∗∗∗ p < 0.0001; ns, not significant (Student's t test or ANOVA followed by Dunnett's post hoc test). Error bars represent SEM.

Article Snippet: The ApoE3 iPSC line was generated from the Coriell Institute's fibroblast line derived from a healthy individual (age 75 years, female; #AG09173) by Dr. Yankner’s Laboratory at Harvard Medical School ( ).

Techniques: Derivative Assay, Staining